Pertussis cough is characterized by a paroxysmal, spasmodic cough with an inspiratory roar like a “rooster’s crow”. The paroxysmal, spasmodic cough is caused by laryngeal edema due to Bordetella pertussis infection. Initially, the cough is more prominent and gradually worsens, often becoming milder during the day and worse at night. As the disease progresses, a more pronounced paroxysmal, spasmodic cough develops, which usually lasts for 2-6 weeks, or up to 2 months or more. The cough is characterized by a series of spasmodic coughs, accompanied by a long, deep inhalation, with a special high-pitched, “cock-a-doodle-doo”-like inspiratory roar. The spasmodic cough may be repeated several times until a large amount of thick sputum is coughed up, sometimes accompanied by vomiting. Pertussis is a contagious acute respiratory disease, mainly caused by Bordetella pertussis infection, and the infected person is the only source of infection. Vaccination against pertussis is effective in preventing infection. If there is a prolonged cough with vomiting, dyspnea, or a “rooster” sound of inspiration, it is necessary to consult a doctor for a definitive diagnosis and early standardized treatment to minimize the adverse effects of the disease.