Many patients’ families feel terrible when they hear the word chemotherapy, and when asked why, most of them reply that they are worried that the death of the patient will be accelerated after chemotherapy. In fact, this is not true. Most of the possible adverse reactions caused by chemotherapy drugs are nausea, loss of appetite and vomiting and other gastrointestinal reactions, which are transient processes, and most patients have relatively mild reactions as long as they pay attention to prevention and symptomatic treatment during chemotherapy and after discharge from the hospital. Moreover, the medical situation now is different from that of more than ten years ago, and antiemetic drugs have been updated and replaced, so most patients do not have serious reactions when these drugs are used reasonably. It is also true that we have encountered some patients who had chemotherapy in surgery for 1 or 2 times after surgery, and their family members reflected that the patients had more obvious nausea and vomiting, but after coming to oncology department, there was no obvious reaction during chemotherapy, which is a problem that should not be ignored, and the reason for this is that the surgeon’s main focus is still on surgery, and the chemotherapy lacks necessary attention, so it is not surprising that the patients reacted greatly. This seems unfair to surgeons, but the fact is that human energy is limited, surgeons put how to improve surgical skills in the first place is completely correct, chemotherapy is really not their main business, so the lack of corresponding treatment in chemotherapy patients is completely understandable. Some patients have obvious loss of appetite and weight loss when they are first diagnosed with tumor, especially for digestive tract tumors, and even obvious anemia. There is no doubt that these symptoms are caused by the tumor. For these first-time patients, if chemotherapy is given before surgery or not suitable for surgery, the above symptoms will disappear after the tumor is controlled, which is a good reflection of the efficacy of chemotherapy, and the patients can live longer and better after the tumor is controlled.