The fusion gene test is chromosomal, which is used to determine the value of chromosomal translocation leading to the occurrence of diseases by detecting the presence of fusion genes in chromosomes.
Through the study and analysis of a large number of chromosomal abnormal hematologic malignancies and related genes, it has been shown that abnormal chromosomes are one of the most important causes of oncogene activation. One of the forms of chromosomal abnormality is fusion gene, which is a recombination of two genes due to chromosomal translocation, and as a result, fusion proteins with transforming activity are produced and expressed.
Clinically, gene fusion testing is usually applied to the diagnosis of leukemia, and patients are advised not to eat too much greasy or high protein food before the test.