The following techniques are used for the treatment of pain: (1) nerve block techniques at various locations; (2) peripheral nerve and stellate ganglion puncture and placement under neurostimulator positioning; (3) peripheral nerve block and placement under ultrasound guidance; (4) various minimally invasive treatments under CT guidance; (1) pterygopalatine ganglion placement for headache; (2) trigeminal nerve radiofrequency disruption for trigeminal neuralgia; (3) stem mammary foramen placement for facial palsy and (4) anterior otolaryngo-pharyngeal nerve disruption for lingual-pharyngeal neuralgia; (5) radiofrequency disruption of the dorsal horn of the spinal cord for neuropathic pain after paraplegia; (6) radiofrequency disruption of the thoracic spinal nerve for postherpetic pain, intercostal neuralgia, and thoracic metastatic cancer pain; (7) transabdominal access to the abdominal plexus for advanced cancer pain; (8) thoracic sympathetic ganglion disruption for spontaneous hyperhidrosis; (9) lumbar sympathetic ganglion placement and disruption for spontaneous hyperhidrosis (9) sympathetic ganglion placement and destruction for treatment of vaso-occlusive vasculitis and neuropathic pain; (10) odd ganglion destruction for treatment of pelvic floor pain; (11) cervical and lumbar disc ozone intervention for treatment of cervical and lumbar disc herniation; (12) bi-directional placement for treatment of giant lumbar disc herniation; (5) C-arm targeted anterior epidural space placement for treatment of chronic neck, shoulder and back pain; (6) central analgesic drug infusion system implantation for treatment of advanced cancer pain Treatment of advanced cancer pain; (7) spinal cord electrical stimulation for intractable low back pain, post-operative lumbar spine pain, neuropathic pain; (8) ozone macroautohemotherapy for gout, hyperlipidemia, angina pectoris, vasculitis and occlusive peripheral arteriosclerotic pain, burn pain, inflammatory infectious pain; (9) ozone knee injection for knee osteoarthritis; (10) ozone epidural injection for neck, shoulder and low back pain.