PEEK cranioplasty is a new comprehensive treatment plan for all kinds of cranial bone repair pioneered by our functional neurosurgery, including not only the repair of the defective bone window, but also the protection of the scalp, temporal muscle and other tissues, and the cosmetic operation of the skull appearance, etc., in order to achieve anatomical integrity, functional perfection and aesthetic appearance, so that patients can return to society with a new posture and embrace The patient can return to society with a new attitude and embrace a good life. First of all, a comprehensive scientific diagnosis and assessment of the patient’s cranial defect and comprehensive condition should be conducted, and a scientific and thorough comprehensive treatment plan should be formulated. A CT scan of the patient’s skull is performed, 3D data is collected, 3D reconstruction is performed, PEEK repair plates are designed, and individualized adjustments are made to the material edges, thickness, and mesh apertures according to the patient’s specific situation to prevent scalp abrasion, ensure adequate postoperative blood flow, and prevent temporal muscle atrophy. During the operation, the scalp was incised, the layers of tissue were finely separated, the bone window was exposed, and the three-dimensional shaped PEEK plate was taken and embedded in the bone window, adjusted and reset, well fixed, complete reset of all layers of tissue, and tissue activity was maintained. And the factors affecting the aesthetic appearance are treated with reasonable cosmetic surgery to achieve the natural aesthetic symmetry after surgery. Patients with cranial defects are suggested to go to regular hospitals early to choose suitable repair materials for cranial bone repair and regain health as soon as possible.