Methylprednisolone belongs to a kind of glucocorticoid, if children apply improperly will cause the following hazards: 1, cause children to appear Cushing’s syndrome, long time high dose application of methylprednisolone, often caused by buffalo back, full moon face, which is due to the glucocorticoid will cause fat redistribution leads to; 2, caused by water and sodium retention, a long period of time to take methylprednisolone will cause the face of the puffy, etc.; 3, caused by the children to appear osteoporosis, because the long time application of glucocorticosteroids will cause the children to lose calcium, and then cause osteoporosis.