Heart failure is one of the serious complications of uremia and an important cause of death in uremia. Uremic heart failure caused by the following main causes: 1, hypertensive heart disease 2, the role of uremic toxins: Uremia when harmful metabolites accumulate in the body, toxins inhibit the myocardium causing cardiomyopathy, resulting in myocardial decompensation and cardiac failure. 3, excessive blood volume: the blood volume increases in uremia, the left ventricular end-diastolic volume, cardiac expulsion and cardiac blood volume increases, when the heart function can not compensate for the left ventricular hypofunction and lead to heart failure. 4, renal anemia: long-term anemia in uremic patients makes myocardial hypoxia, myocardial function decreases, because the body compensates to speed up the heart rate and increase the volume of cardiac excretion, the heart can lead to heart failure due to overload and myocardial hypoxia over time. 5, electrolyte metabolism disorders and acidosis: Uremia due to electrolyte disorders make myocardial electrical activity and excitability changes, which leads to arrhythmia and heart failure. 6, atherosclerosis: hypertension complicating uremia and hyperlipidemia occurring after dialysis can accelerate the progression of atherosclerosis and increase the mortality rate of uremia, and death is often caused by myocardial infarction during the dialysis process. 7, low immunity: low immunity in uremia can easily cause infection and cause post-infection myocarditis or pericarditis resulting in heart failure. 8, dialysis with arteriovenous fistula: because of the large arteriovenous blood flow, increasing the load on the heart, which can lead to heart failure in the long run. The diagnosis and treatment of uremic heart failure is similar to that of general heart failure, but the efficacy is often poor. The main therapeutic measures include: 1. limiting the intake of water and sodium. 2, the use of diuretics: generally choose fast and strong diuretics, and the dosage should be large, to increase the discharge of water and sodium, reduce the load on the heart. 3, digitalis: it is appropriate to use digitalis drugs with a short half-life, and applied in reduced amounts according to the creatinine clearance rate. 4, vasodilators: For patients with congestive heart failure with low cardiac output and those who have poor results with diuretics and digitalis, especially those with significant hypertension, the effect is particularly good. In addition, nitrates can be applied to increase the venous volume and reduce the amount of blood returned to the heart, so that the diastolic filling pressure of the heart decreases and pulmonary stasis is reduced. Of course, treatment of the primary disease is most important, and dialysis treatment should be preferred.