The generic name of the supplement is estradiol valerate tablets, and taking estradiol valerate improves cervical mucus. Estradiol valerate can be used in combination with progesterone to establish an artificial menstrual cycle. It can also be used to supplement estrogen deficiency associated with natural or artificial menopause, such as vasodilatory disorders, genitourinary nutritional disorders, and psychiatric disorders, and it can also play a role in improving cervical mucus. Cervical mucus is the fluid secreted by cervical gland cells under the influence of androgens and progesterone, which may be mixed with small amounts of endometrial and tubal mucosal secretions and incorporated into vaginal secretions. Its formation may be due to physiological phenomena, cervicitis, cervical cancer and other factors. Adverse reactions such as breast distension, stomach upset, nausea and headache may occur after the use of estradiol valerate. It needs to be contraindicated in patients who are pregnant as well as breastfeeding women, undiagnosed vaginal bleeding, known or suspected breast cancer, known or suspected precancerous lesions or malignant tumors affected by sex hormones.