Immunoglobulin (immunoglobulin) refers to animal proteins with antibody activity. It is mainly found in blood plasma, but also in other body fluids, tissues and some secretory fluids. Serum immunoglobulin (Ig) includes: IgG, IgA, IgM, IgD, IgE. its normal range: IgG 7, 6 ~ 16, 6g/L; IgA 0, 71 ~ 3, 35g/L; IgM 0, 48 ~ 2, 12g/L; IgD 0, 01 ~ 0, 04g/L; IgE 0, 001 ~ 0, 009g/L. So, how to prevent Multiple myeloma causing serum immunoglobulins can be elevated? The following is a brief introduction: 1. You should eat high-calorie, high-protein, vitamin-rich and easy-to-digest things. Patients with renal insufficiency should eat low sodium, low protein and wheat starch to reduce the burden on the kidneys. Like when there is hyperuricemia and hypercalcemia, patients should be motivated to drink more water and hold the daily urine volume above 2000ml to prevent or reduce hypercalcemia and hyperuricemia. 2, usually the patient can exercise in moderation, excessive inhibition of the body can make the patient secondary infection or osteoporosis, but never be able to do strenuous exercise, in order to prevent the load is too heavy, to prevent falls, bruises, depending on the exhaustive condition let use waist girth, splint, but to prevent the resulting poor blood circulation. If the patient is prone to comorbidities due to prolonged exertion, the immune function of the body decreases, bed rest should be taken and activities should be reduced. When there is bone destruction, absolute bed rest should be taken to prevent leading to pathological fracture. 3. Contact with carcinogenic factors should be avoided. Protection of multiple myeloma should be done well. If there is contact with patients with similar history and symptoms, regular physical examination should be conducted to be able to detect and treat actively at the early stage. Patients are suitable to participate in moderate amount of regular activities to reduce decalcification. Pay attention to personal hygiene to prevent infection, especially to pay attention to the oral mucosa and skin cleaning, to prevent colds. 4, help patients to say their own concerns, better attention and care, try to ease the patient’s mental stress, help patients to face reality, get rid of panic, so that the mood is stable. It is connected to the environment, diet and other reasons. Therefore, it is important to protect multiple myeloma detection, strengthen the physical fitness of patients, timely treatment of chronic diseases, and avoid the exposure to radiation and chemical toxins.