The first thing you need to do is to take a blood test to check the HCG value to rule out pregnancy-induced amenorrhea. If pregnancy-induced amenorrhea is ruled out, further examination of sex hormone six and gynecological ultrasound is needed. If the sex hormone six tests are within the normal range, and the gynecological ultrasound endothelial thickness is not less than 0.5cm, for this case can be progesterone withdrawal treatment. Generally, progesterone injection 20mg, once a day, intramuscular injection, continuous application for 3 days, stop the drug and wait for menstruation, in most cases within 2 weeks of stopping the drug will have menstruation. If the patient’s sex hormone profile is suggestive of postmenopausal levels, sex hormone replacement therapy should be considered in this case.