Patients with Hashimoto’s thyroiditis are generally not treated with prednisone. The cause of Hashimoto’s thyroiditis is not clearly defined and is usually thought to be due to the interaction of immune, genetic and environmental factors. Hashimoto’s thyroiditis can have no obvious clinical symptoms in the early stages of the disease, but as the disease progresses, the thyroid gland may become enlarged, fatigue, fear of cold, memory loss, loss of appetite and other clinical symptoms. There is no specific treatment for Hashimoto’s thyroiditis. If there is only goiter and no hypothyroidism, treatment is usually not needed. Those with obvious goiter or hypothyroidism need to take levothyroxine replacement therapy. Surgery may be considered for those with significant compression symptoms that are not relieved by levothyroxine therapy. Those with thyrotoxicosis are treated symptomatically with beta-blockers. It is usually treated without prednisone. If you are suffering from Hashimoto’s thyroiditis, while actively treating the disease, you should follow up regularly according to the doctor’s instructions to understand the progress of the disease, and the main checkups include thyroid function and thyroid ultrasonography.