Although the name “leukemia” does not exist in Chinese medicine, acute leukemia is often classified as “hot labor”, “acute labor”, and “blood evidence” based on its rapid onset, fever, hemorrhage, anemia, and enlarged lymph nodes in the liver and spleen. The symptoms of acute leukemia include “hot labor”, “acute labor”, and “blood evidence”. The pathological changes are mainly the proliferation and infiltration of leukemia cells, bleeding, tissue malnutrition and necrosis, secondary infection, and the effect of anti-leukemia treatment. According to Chinese medicine, acute leukemia is caused externally by the presence of evil toxins (fetus toxins, heat toxins); internally by the weakness of the righteousness, or the lack of endowment, fatigue, injury by diet, internal organ disorders, or injury by emotion. Children are more sensitive than adults to external viruses, bacteria or chemical drugs, or radiation and other evil and toxic factors. Whenever the body is deficient in positive qi, or the congenital “fetal toxin” is already inside, the evil toxin invades inside or the toxin develops from inside, the evil contains in the bone marrow, the bone marrow is damaged, the evil of heat toxin evaporates from the bone marrow to the outside, diffuses into the three jiao, the internal organs are stagnant, and the qi is hot. Injury to Ying Yin, damage to bone marrow, blood deficiency; heat and toxin fumigation, burning the veins and collaterals, forcing the blood to move; or internal obstruction of blood stasis, stagnation of the meridians, heat and stasis, blood does not follow the meridians, or due to prolonged depletion of qi and blood, qi deficiency can not take in blood, forming blood evidence; pure Yang body, after feeling the evil, easily from heat, blood heat incandescence and high fever persists; heat and toxin refine fluid into phlegm, phlegm and heat toxin, intertwined as a problem. The evil toxin lurks in the meridians and obstructs the flow of qi and blood, stagnating qi, blood and phlegm, which can form lumps under the ribs, enlarged liver, spleen, lymph nodes and bone pain. In children, the liver often has a surplus of evil toxins, which invade the sympathetic yin, the liver yang rises and reverses, and disturbs the clear orifices, resulting in headache, dizziness, vomiting, neck straightening, even convulsions and coma. The evil toxin is deep in the bone marrow, and over time, it burns the essence and blood, which can lead to loss of yin and yang qi and blood. After treatment, the disease can be relieved when the evil toxin changes from strong to weak and the righteousness is gradually restored; as the evil toxin is not yet exhausted, when the righteousness is internally deficient, the disease is prone to recurrence. In summary, heat toxicity, phlegm coagulation, blood stasis, and Zheng deficiency are the cause and effect of this disease, forming a mixed evidence of deficiency and actuality, which runs throughout the disease. This toxin also has an important characteristic, that is, it is easy to deep-rooted in the body, lingering, difficult to get rid of, the residual toxin accumulates in the body, depleting the vital energy, for the tiger as a despair, this is the fundamental reason for the leukemia is difficult to heal and easy to relapse after remission, and is also the biggest difference with other warm-heat toxins. This is the fundamental cause of leukemia, which is different from other warm toxins. 2. 2. 1 Evil toxin is strong, and phlegm and stagnation of phlegm and stagnation of phlegm are comparable to the early stage of the disease, without chemotherapy or chemotherapy induction. The disease is characterized by the predominance of evil and positive, or the deficiency of positive is not obvious. Symptoms: rapid onset, intense heat and thirst, headache, burning lips, epistaxis or blood in urine or stool, petechiae on skin, red urine, constipation, scrofula and phlegm nuclei, or hard and full lumps under the dorsum, soreness and pain in the sternum, or even delirium, or sores on the mouth and tongue, sore throat, swollen gums, yellow sputum from cough, burning pain in the anus. The tongue is red and vivid or with petechiae, the coating is yellow and greasy, and the pulse is counted or astringent. At this stage, the evil toxin is already strong, but the positive qi has not yet decayed, the evil and the positive are competing, the heat is strong and injures the fluids, the blood is disturbed, the blood is forced to travel, and even the evil toxin obscures the heart orifice; the heat toxin decocts the fluids into phlegm, congests the bone marrow, stagnates the ligaments, obstructs the flow of qi and blood, and stagnates in the hypochondrium, in the side of the neck, in the armpit, in the crotch and abdomen. This is the most critical point. The main treatment is to expel the evil, using the method of clearing heat and removing toxins, activating blood circulation, resolving blood stasis and dispersing phlegm. The formula: Qing Dai (for douche) 3~6 g, Half Branch Lotus, White Flowered Snake Tongue Cress 15~20 g each, Red Peony, Sandy Bean Root, Roasted Turtle A (first decoction) 5~10 g each, Xian He Cao, White Mao Root, Tiger Balm, Xia Ku Cao 10~15 g each, 1 dose daily, decoction with water. 2. 2. 2 The evil toxin is gradually receding, and the deficiency of both qi and yin corresponds to the middle stage of the disease or the consolidation and intensification stage after remission. The disease is characterized by the deficiency of the body and the absence of the evil, and the symptoms of the disease are the same. Symptoms: low fever that does not subside, or late afternoon hot flashes, irritability of the five hearts, dizziness and tinnitus, sweating and weakness, weakness of the limbs, nausea and vomiting, subcutaneous petechiae, epistaxis, dryness of the oropharynx, pain in the body and bones, shrinking or disappearing of the lump under the throat. The tongue is red or light red, with little coating, and the pulse is fine or weak. At this stage, although the evil toxin is gradually receding, the positive qi has been damaged, the internal depression of the heat toxin for a long time is bound to consume qi and injure yin; water does not contain wood, the liver and kidney are deficient in yin and blood; the deficiency fire grows, internal heat is fumigated, damp-heat is contained, the spleen and stomach are damaged, transportation and transformation are not normal, and qi is not descending. At this time, the symptoms are the same, the disease is still heavy, and it is easy to feel the guest evil. The treatment is to support the positive and dispel the evil, treating both the symptoms and the root cause, using the method of benefiting Qi and nourishing Yin, detoxifying and resolving blood stasis, strengthening the spleen and harmonizing the stomach. The formula: Radix et Rhizoma Ginseng, Radix Angelicae Sinensis, Radix et Rhizoma Dioscoreae 10~15 g each, Radix Astragali, Radix et Rhizoma Polygonati, Radix et Rhizoma Drynariae, Radix et Rhizoma Semen Nobilis, Radix et Rhizoma Atractylodes Macrocephalae 5~10 g each. 2. 3 Insufficient Qi and Blood, Yin and Yang deficiency The disease is characterized by a deficiency of Qi and Blood, which corresponds to the late stage of the disease or the maintenance treatment after remission. The disease is characterized by the absence of evil and the deterioration of positive deficiency. Symptoms: yellowish or pale face, lassitude, palpitations, shortness of breath, especially when moving, sweating, lack of warmth in the limbs, pale lips and nails, sluggishness, false irritability, or petechiae. The tongue is pale, fat or with tooth marks, with thin white fur, and a weak or thin pulse. In this period, although the evil toxin is mostly gone, the Qi and blood then deficient, the spleen and stomach weakness is the Qi and blood biochemical lack of sources, not to nourish the organs, limbs and bones; prolonged exertion, lung Qi is more deficient, Qi and blood deficiency, the heart and soul loss of nourishment, drumming weakness; kidney Qi deficiency, lack of Qi nourishment, bone marrow empty; liver and kidney Yin deficiency, essence does not turn blood, or even Yin loss and Yang, essence and Qi two injuries. At this time, the positive energy has not been restored, the remaining evil has not been cleared, easy to relapse. The main treatment is to support the righteousness and clear the residual evil at the same time, using the method of nourishing the blood, benefiting the kidney and filling the marrow, and supporting the righteousness to resolve the poison.