Small cell neuroendocrine carcinoma targeted drugs have little effect. Small cell lung cancer is a special type of lung cancer with neuroendocrine function, which is sensitive to radiotherapy and chemotherapy, but easy to recur and metastasize, with poor prognosis. Its main treatment methods include surgery, chemotherapy, radiotherapy, etc. At present, there is no more effective targeted drug. If small cell neuroendocrine carcinoma patients have surgical indications, surgery should be preferred, and the operation scope should be enlarged appropriately. After surgery, patients can be treated with simultaneous radiotherapy and chemotherapy, and commonly used chemotherapeutic drugs include etoposide, etc. If surgery is not suitable, radiotherapy can be used. If surgery is not suitable, radiotherapy can be used to slow down the disease progress. It is recommended that patients under the guidance of the doctor active treatment, maintain a good state of mind, in order to extend the survival period.