Statins are not only effective in lowering cholesterol, but also in stabilizing and reversing plaque. Therefore, it has now become a commonly used drug for patients with atherosclerotic cardiovascular disease. For high blood fat and in order to prevent the occurrence of cardiovascular disease, is the need to consider long-term use of statin. Although statin drugs are good, but if you take them for a long time, there are still some potential risks. Therefore, it is important to have a checkup after taking statins for a long period of time. The purpose of the checkup is to find out how effective and safe the statin is. The first check-up should be within 1-2 months after taking statin. It is important not to wait too long between the first checkups. It is also important to realize that the purpose of the first test is for the doctor to know if the amount of statin being taken is appropriate, if the lipid targets are being met, and if some of the side effects of the statin are within acceptable limits. After that, you can review the test every 1-2 months, and the blood lipids and statin side effects are stable, and then you can review the test once every six months or so. Then the checkup items after taking statin for one year are as follows: i. The risk of elevated blood glucose caused by statin is about 10%, so checking whether blood glucose is elevated is needed. Second, check the blood lipid level, different blood lipid level and accompanying diseases, different requirements for the target value of blood lipid; if the blood lipid does not meet the standard, it is possible to need to adjust the dosage or change the drug. Third, long-term use of statin is easy to cause damage to kidney function, so kidney function check is not to be ignored, which directly affects the dosage of statin. Fourth, the incidence of persistently elevated aminotransferase levels during statin therapy is 0.5%-3.0%. Therefore liver function tests are also required. Fifth, liver enzymes and muscle enzymes, statin side effects are more common and important is the effect of statin on liver enzymes and muscle, if there is muscle pain after taking statin, review at any time. Sixth, pay attention to whether there is muscle pain, skin weakness, whether there is itching, rash, joint pain, insomnia, etc., and the usual blood pressure is also need to pay attention to.