Early Down, or Early Down Syndrome Screening, usually produces results in 7 to 10 days. The time it takes to get the results after a Down’s syndrome screening varies from hospital to hospital depending on the process, and is usually less than within 7 working days and more than about 10 days. The combined early and mid-pregnancy screening program has the highest Down syndrome detection rate and the lowest false positive rate of any screening program available. Down syndrome is one of the most common chromosomal disorders in humans, a triple mutation of chromosome 21 that results in multi-organ and multi-system abnormalities, with a birth incidence of 1:700 to 1:900. The risk of having a Down’s syndrome baby increases with the mother’s age, reaching 1:430 over the age of 35 and 1:45 over the age of 45. Screening for Down syndrome is done at 11 to 14 weeks of pregnancy. It is usually determined by ultrasound and serum indicators of fetal posterior nuchal translucency (NT) screening. At 11~14 weeks of pregnancy, a nullus echogenicus band will appear at the back of the fetal neck, and the normal value of NT on ultrasound is less than 2.5 millimeters. If the NT is more than 2.5 mm, it will be judged as thickening, suggesting that the fetus may have abnormal heart structure or bone development or chromosomal abnormality, and further amniocentesis is needed to exclude fetal chromosomal abnormality. If the fetal chromosomes are normal by amniocentesis, the fetal heart and bone development should be further monitored, and the risk of Down’s syndrome should be estimated by various serologic indicators. If the screening result is high risk, it is recommended to consult a medical professional for timely treatment.