The elderly perianal secretion of moist liquid may be anal fistula, external hemorrhoids, perianal abscess, etc., the cause of different, the treatment is also different; but the above diseases can not play a therapeutic role in taking medication, the majority of cases need to choose the surgical treatment. Anal fistula is the anal canal or rectum and perineal skin connected to the formation of a granulomatous tube, the main symptom is the fistula of the external mouth of the discharge of pus, blood or mucus secretion. Most fistulas require surgery because they are difficult to heal on their own. Current surgical procedures include fistulotomy, hanging thread therapy and anal fistulotomy. The main clinical manifestations of external hemorrhoids are discomfort, moisture and sometimes itching in the anal area. For external hemorrhoids, if there are no symptoms, they can be left untreated; if they are symptomatic, they can be treated at an early stage by conservative treatments such as adjusting diet and bowel habits, hot water sitz baths, etc., and those who are not effective can be surgically removed. Patients with perianal abscesses need to undergo surgery and incision and drainage to treat them. If you feel unwell, please consult a doctor to clarify the cause of the problem and receive appropriate treatment.