One nostril is ventilated and the other is not ventilated may be caused by chronic simple rhinitis, nasal polyps, deviated septum and other diseases, the patient needs to follow the doctor’s instructions for medication, general measures, etc., and if necessary, surgical treatment is also needed. 1. Chronic simple rhinitis: saline can be used to clean the nasal cavity, and local use of budesonide, mometasone furoate and other hormonal drugs. 2. Nasal polyps: Usually, patients can follow the doctor’s instructions to use glucocorticoid medication such as budesonide nasal spray and trimethoprim nasal spray. If the effect of conservative treatment is unsatisfactory, nasal endoscopic surgery can be performed after the doctor’s evaluation. 3. Deviated septum: Usually, patients need to keep the nasal cavity moist and use topical nasal drops such as peppermint oil, and also need to pay attention to the protection of the nose, avoiding external stimuli such as nose picking. For patients with obvious symptoms, they need to undergo septal submucosal corrective surgery under the guidance of a doctor. It is recommended that patients with one nostril ventilated and one not ventilated should actively seek medical advice to find out the cause of the disease and standardize the use of medication and treatment.