Sildenafil is an on-demand drug that can be taken up to once a day and 3 times a week, and generally does not have a significant impact on the body. Sildenafil enhances the nitric oxide (NO)-cGMP pathway through selective inhibition of PDE5, elevating cGMP levels and leading to relaxation of penile cavernous smooth muscle, so that patients with erectile dysfunction produce a natural erectile response to sexual stimulation. It is mainly used clinically for the treatment of erectile dysfunction. This product is recommended to be taken as needed before sexual activity and used up to once a day. Therefore, it is possible to take Sildenafil 3 times a week, but it is recommended to take it on alternate days and not to use it continuously every day in case the drug is not fully metabolized and causes related adverse reactions. Adverse reactions that often occur after the use of sildenafil include nasal congestion, flushing, dyspepsia, dizziness, rash, visual abnormalities, etc. It is prohibited for those who are allergic to this product, and this product should not be used in combination with nitrate drugs in order to avoid the occurrence of hypotension. If erectile dysfunction exists, it is recommended to consult a physician first and use the drug according to the doctor’s instructions, and should not be used blindly.