Oral lichen planus does not heal itself for 30 years. Oral lichen planus is a stubborn and highly recurrent disease that cannot yet be cured. However, it is possible to eliminate symptoms, control the disease, reduce recurrence, and generally have a good prognosis. At present, the etiology of oral lichen planus has not been fully elaborated, so there is no specific treatment method. Clinically, according to the patient’s local and systemic conditions, remove local irritants, supplemented with drug therapy such as supplemental vitamin E, but also the use of immunosuppressants and immunomodulators, such as chloroquine phosphate, adrenal cortical steroids and cytotoxic drugs, thymosin and so on. For long-term erosion does not heal, can be localized use of prednisolone suspension 0 treatment, the range of smaller lesions can be surgically removed. It should be noted that this disease is a potentially malignant disease, there is a certain chance of cancer, if there is a long period of time, you need to actively review the situation. The above medications should be used under medical supervision.