There is no “best combination of Codonopsis pilosula”. Codonopsis can be combined with Astragalus, Angelica sinensis, Ophiopogon, Schisandra chinensis, and so on. Radix Codonopsis pilosula has the effect of tonifying the spleen and lungs, nourishing blood and promoting the production of body fluid. It can be used to treat deficiency of spleen and lung qi, deficiency of qi and blood, yellowish complexion (yellowish color without luster), thirst due to injury of fluid, palpitation (rapid heartbeat often accompanied by panic), shortness of breath, etc. It can be used to treat the symptoms of deficiency of qi and blood. It can be combined with Angelica sinensis, Radix Astragali, Radix Rehmanniae Praeparata, etc. for the treatment of deficiency of qi and blood such as yellowish color of the face, palpitation and dizziness, and tiredness of the limbs. It can be combined with Fructus schisandrae chinensis and Fructus melliferae if it is used to treat thirst and thirst due to internal heat (internal heat accompanied by excessive eating, drinking and urination, etc.) caused by deficiency of Qi and Jin. Dangshen should not be used in solid or hot cases where the positive qi is not deficient; it should not be used with veratrum. The adverse effects of Radix Codonopsis pilosulae are not clear. If you need to use Codonopsis pilosula with other medicines, you should consult your doctor first and use the medicine under the doctor’s guidance.