Cold feet and knees can be caused by blocked arteries, diabetes, herniated lumbar discs and other factors. It can be improved by medication and surgery under doctor’s guidance. 1. Blocked arteries: Arteries can supply blood and oxygen to local tissues. Since arterial blood is rich in heat, when arteries become blocked, cold feet and knees may occur. Symptoms can be improved by medication with artery-dilating drugs such as verapamil, irbesartan and captopril. 2. Diabetes mellitus: If diabetes mellitus has poor long-term blood sugar control, it may lead to nerve dysfunction in the lower limbs, and cold feet and knees may occur due to abnormal nerve discharges. The symptoms can be relieved by medication and the use of hypoglycemic drugs, such as metformin, glibenclamide, reglaneride and so on. 3. Lumbar disc herniation: When lumbar disc herniation occurs, the protruding nucleus pulposus may irritate the surrounding nerve roots, causing abnormal sensation in the lower limbs and cold feet and knees. Symptoms can be relieved by surgical treatments, such as hemilaminectomy-nucleus pulposus removal, minimally invasive disc removal, and percutaneous endoscopic lumbar discectomy. When cold feet and knees occur, you should seek medical attention and under the guidance of your doctor, undergo tests such as vascular ultrasound, fasting glucose measurement, MRI, etc. to clarify the cause of the disease and treat it aggressively.