Explosive liver is a medical term for acute liver failure due to non-pathologic causes. The patient is usually healthy, without family genetic history and other diseases, and suddenly develops acute liver failure. Acute liver failure is characterized by a rapid onset of disease, and liver failure symptoms characterized by hepatic encephalopathy of degree II or higher can appear in a short period of time, so it is called acute liver failure caused by non-pathological reasons. Treatment of acute liver failure is divided into general treatment, treatment of complications, liver transplantation, artificial liver support therapy, hepatocyte transplantation and stem cell transplantation. General treatment includes bed rest, nutritional support, protection of liver cells and improvement of hepatic microcirculation, and promotion of liver cell regeneration. If the patient has any discomfort please seek medical treatment in time to avoid delaying the condition, which may lead to aggravation of the condition.