Rheumatoid factor is only a laboratory indicator, and there is no such thing as a symptom of high rheumatoid factor. However, a rheumatoid factor value higher than the upper limit of the normal reference range often suggests that the patient may have rheumatoid arthritis, systemic sclerosis, systemic lupus erythematosus and other diseases, and different types of diseases may lead to different symptoms. Rheumatoid factor is an lgM-type anti-degenerative lgG antibody. Rheumatoid factor measurements higher than the upper limit of the normal reference range often suggest that patients may have rheumatoid arthritis, systemic sclerosis, systemic lupus erythematosus and other diseases, and different types of diseases may lead to different symptoms. For example, the common symptoms of rheumatoid arthritis are morning stiffness, joint swelling, joint pain, etc. The common symptoms of systemic lupus erythematosus are butterfly-shaped erythema, joint pain, fever, alopecia, light allergy, etc. The common symptoms of systemic sclerosis are hard spots on the skin and Raynaud’s phenomenon. Patients with high rheumatoid factor need to go to the rheumatology and immunology department of regular hospitals, and further improve autoantibodies, CT, blood sedimentation, CRP and other related auxiliary tests under the guidance of doctors to make a clear diagnosis, and then treat the cause of the disease.