Lymph nodes 2 cm with clear borders are usually not malignant. If malignant changes occur in the lymph nodes, there will usually be local hypo-differentiation of tissue cells, and also infiltrative growth to the surrounding normal tissues, and sometimes ulceration may also occur, and will not appear lymph nodes 2 cm and clear boundaries of the manifestations. If there are lymph nodes 2 cm clear border performance, most cases belong to benign proliferative lesions, such as lymphadenitis, connective tissue disease, etc., can follow the doctor’s advice to be treated accordingly. If it is lymphadenitis, you can take amoxicillin, cefaclor and other antibiotics; if it is caused by connective tissue disease, you can take prednisolone, interferon and other drugs. If there is no obvious discomfort, it is generally recommended to take a light diet and active observation, you can also follow the doctor’s instructions to take Xia Gu Cao granules and other proprietary Chinese medicines to actively regulate, it is possible to make the enlarged lymph nodes gradually dissipate. If the lymph nodes are 2cm in size and have clear boundaries, it is best to carry out pathological biopsy in time to further clarify the diagnosis. If the lymph nodes continue to increase in size in the later stage, it is recommended to seek medical treatment as soon as possible to carry out surgical resection of the diseased tissues to avoid malignant changes in the later stage.