Generally speaking, the analgesic effect of painkillers should be based on the cause and nature of the pain to choose the appropriate painkillers so as to achieve the best pain relief effect. 1. Non-steroidal anti-inflammatory drugs: there are ibuprofen, acetaminophen, etc., generally used for common pain, such as toothache, menstrual cramps and so on. 2. Central painkillers: such as Tramadol, commonly used for acute pain, postoperative pain, etc. 3. Narcotic painkillers: such as morphine, dulcolax, commonly used in patients with cancer pain, long-term use of such drugs or improper use will lead to addiction, special attention should be paid. All the above medicines should be taken under doctor’s guidance and in strict accordance with doctor’s prescription, and should not be used by oneself or change the dosage, so as to avoid serious consequences.