Often men can use medications such as Dapoxetine and Lidocaine to make sex last a little longer, as prescribed by their doctor. Often men can follow the doctor’s advice with selective 5-hydroxytryptamine reuptake inhibitors to make sex more durable, such as dapoxetine, fluoxetine, paroxetine, sertraline and so on, help to prolong the time of ejaculation. Some men are prone to accompany nausea and vomiting, headache, dizziness, diarrhea and other adverse reactions after applying such drugs. Some men can also use local anesthetic drugs on the surface of the penis, such as lidocaine, proparacaine, etc., which helps to reduce penile sensitivity and can prolong male ejaculation time, prompting sex life a little more durable. It is worth noting that some men may experience penile numbness or allergy after using the drug. It is recommended that men use the medication under the guidance of a doctor, and should not use the medication on their own to prevent accidents from occurring. Men should also pay attention to avoid long-term use of drugs to prevent the formation of drug dependence.