Watermelon cream spray can be applied to children with mouth ulcers and herpes pharyngitis, when the mouth is very painful, salivation or drooling, poor mental state and often accompanied by fever. At this time, in addition to the application of oral medication, topical treatment with watermelon cream spray can be used. Watermelon cream spray can be sprayed directly on the patient to effectively reduce pain, which is more acceptable to children. The side effects of watermelon cream are relatively mild and safe, so it is suitable for children to apply it many times. The course of application of watermelon cream spray for children is about a week, and the condition can be significantly improved within a week. Parents can be assured that the application to children, do not think that the application of watermelon cream spray is more harmful.