The surgical incision for appendicitis is chosen, often at the site of the right lower abdominal Mac’s point, which is the intersection of the umbilicus and the middle and outer 1/3 of the right anterior superior iliac spine connecting the umbilicus. The incision is chosen to be perpendicular to the line of conjunction, and traditionally a McIlroy’s incision may be chosen for surgery. In patients with an inaccurate preoperative diagnosis or suspicion of other systemic diseases as well as in women, an exploratory incision at the outer edge of the rectus abdominis muscle on the right side can also be chosen, as it facilitates intraoperative maneuvering. If co-morbidities are detected, including diverticulitis or gynecologic diseases, like torsion of the ovarian cyst tip or ovarian abscess, the incision can be appropriately lengthened to facilitate surgery. For patients undergoing laparoscopic surgery, there is a marked difference in the choice of incision, including a single transumbilical maneuver, as well as auxiliary maneuver holes in the left lower abdomen and right lower abdomen.