Children with fever, cold hands and feet shivering, in the early stage of the rise in body temperature, blood vessels and skeletal muscle contraction, manifested in the phenomenon of “cold hands and feet shivering”. In pediatrics more diseases, such as acute respiratory tract infections, intracranial infections and other diseases, can appear fever symptoms, mostly due to children’s thermoregulatory center development is still immature, susceptible to pathogenic infections and other factors, the emergence of fever symptoms. In the early stage of temperature rise, involuntary contraction of skeletal muscles can occur, and children can show “shivering”, i.e., chills, and peripheral vasoconstriction can also occur, and there is a manifestation of “cold hands and feet”, which belongs to the body’s physiological response, and at this time, some infants and young children are prone to convulsions. The symptoms, need to monitor the body temperature, discretionary fever. Children with fever and cold hands and feet shivering, there may also be other reasons, it is recommended to go to the hospital in time to improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.