Mixed purpura is the most severe and more difficult to treat. Often it can be combined with arthritic purpura, abdominal purpura, and renal purpura. In clinical treatment, it is necessary to administer 200 ml of compound monoammonium glycyrrhizinate Sodium Chloride Injection once a day. If the effect is not satisfactory, it is also possible to administer Methylprednisolone Injection, Dexamethasone Injection Glucocorticosteroid Injection to strengthen the effect of anti-inflammatory and immunosuppressive, which is calculated according to the per kilogram of body weight, and the specific conditions need to be determined by the doctor in the interview. If the effect is not very satisfactory after a period of treatment, it may be necessary to apply second-line immunomodulatory drugs, such as tretinoin tablets or cyclosporine A soft capsules for treatment, before and after the treatment need to regularly monitor the blood routine, urine routine, stool routine, liver and kidney function and other laboratory results.