The local appearance of meatball after left heel melanoma excision may be caused by the proliferation of scar granulation tissue or tumor recurrence after surgery localization. After left heel melanoma excision, there will be a certain range of localized tissue loss, which can stimulate the surrounding skin and soft tissue cells to reactive proliferation, and the proliferating multiple cells pile up in the localized area of the defect, and slowly form a meatball-like mass of granulation tissue to fill in the tissue loss left behind after the surgery, and with the passage of time, the surface of which will be scabbed off, forming a localized scar. In addition to the proliferation of scar tissue, the localized appearance of meatballs after left heel melanoma excision may also be caused by incomplete tumor resection, resulting in tumor recurrence. The degree of malignancy of melanoma is high, if the meatball is found in the local tissue after resection, it is necessary to go to the hospital in time to find out the reason and follow the doctor’s advice to treat it actively.