Cleft lip and cleft palate are the most common congenital malformations of the oral and maxillofacial development, accompanied by severe physical defects and various psychological problems. The psychological status of patients with cleft lip and palate during infancy, school age, adolescence and adulthood is somewhat different from that of normal people. Psychological factors play a very important role in disease and health. Therefore, the medical staff of our department sees the patient as a unified body and mind, and pays attention to not only the pathological and physiological changes of the patient, but also the psychological state of the patient, in order to facilitate the postoperative recovery and improve their quality of life. The following will answer questions about the psychological aspects of cleft lip and palate patients from three aspects. 1. Patients with cleft lip and palate bring a heavy psychological blow to their families and caregivers at the beginning of their lives, and if the psychological problems of parents are not corrected, they will directly affect the psychological development of the patients, resulting in a series of psychological problems at an early age. 2. During the frequent and regular sequential treatment of cleft lip and palate patients, health care providers focus more on the impact of treatment methods on function, morphology and growth and development, ignoring the psychological problems of patients. 3. During socialization, strange looks and behaviors from the surrounding crowd cause low self-esteem and inability to perform normal social behavior, which in turn leads to the psychological tendency to deny oneself and refuse to accept oneself. Psychological characteristics of cleft lip and palate patients 1. 0-18 months is an important period for infants to establish secure mother-infant attachment, because of the presence of deformities, the inability to establish normal breastfeeding methods, coupled with the mother’s anxiety and negative psychological state about the deformities of the affected child, will have an important impact on the early psychological development of the affected child. 2. After the age of 6 years, the child begins to develop self-awareness, and abnormalities in language and lip and nose morphology can have a significant impact on the child’s psychological development. Some studies have shown that patients with cleft lip and palate have more pronounced protective behavioral inhibition, are less likely to interact with others, and most patients have low expectations for quality of life. 3. Excessive concern of patients’ families about the patients’ deformities and multiple medical consultations cause anxiety and excessive concern about their appearance, which leads to depression. Third, the psychological intervention pathway for cleft lip and palate patients 1. First, as parents, they should influence their children with a positive, healthy and positive attitude, tell their children about their defects in time and give them positive and positive guidance, which is beneficial to their children’s psychological health. 2. Secondly, parents should first recognize that cleft lip and palate is a very small deformity that has no effect on physical development and intellectual development, and gradually make their children also recognize this problem, face it together, understand it correctly and face life positively. You can look for characters who have the same disease and influence your child with their positive deeds. 3. Finally, you can seek the help of a psychologist when necessary to jointly channel the child’s psychology, and be sure to recognize that appearance and psychology are important together.