Rabeprazole may cause a rise in aminotransferases. Rabeprazole belongs to the proton pump inhibitor class of drugs, this kind of drug may lead to adverse reactions in the liver area, such as fulminant hepatitis, liver dysfunction and jaundice, this kind of situation will lead to transaminase rise. If the transaminase is elevated after using rabeprazole, the drug should be stopped immediately, and usually after stopping the drug, the transaminase will gradually return to normal. In addition to elevated aminotransferases, rabeprazole may also cause some other adverse reactions, such as shock, allergy, and pancytopenia. Also patients with a history of allergy to the ingredients of this product or patients taking atazanavir sulfate should not use rabeprazole sodium. Transaminase rise should be timely communication with the doctor to clarify the specific reasons for the rise in transaminase, for the use of medication should be strictly comply with the doctor’s instructions, can not blindly use their own.