Endometrial clear cell carcinoma is more serious. Endometrial cancer can be categorized into type I and type II, with type I being related to estrogen dependence and type II being non-estrogen dependent. Endometrial clear cell carcinoma belongs to one of the two types, which has no clear relationship with estrogen, and is a relatively rare type of endometrial cancer. This type of endometrial cancer is highly malignant, poorly differentiated, and has rapid distal metastasis, which will spread through direct spread, lymphatic metastasis, and hematogenous metastasis in a short period of time. Most of the patients are already in advanced stage when they are found. If there is uterine enlargement combined with accumulation of pus in the uterine cavity, there can be obvious pressure and pain, and there can be prolapse of cancerous tissues in the cervical canal, which can bleed easily, leading to serious symptoms such as severe lower abdominal pain, cramp-like pain, anemia, emaciation, etc., and the prognosis is not good. Endometrial clear cell carcinoma is more serious, it is recommended to seek medical treatment in time and should be treated actively if diagnosed. It is recommended to consult a professional doctor for specific cases.