Linco means lincomycin, and sulfa means sulfonamide antimicrobial drugs, such as sulfadiazine and sulfamethoxazole. Lincomycin with sulfa drugs can treat streptococcal infections. But it needs to be used under doctor’s guidance. 1. Lincomycin: the drug for the inhibition of bacterial protein synthesis, antibacterial effect on gram-positive bacteria, including erythromycin-sensitive meningococcus, streptococcus, streptococcus pneumoniae, green streptococcus, staphylococcus aureus has a role. It is not sensitive to yeast, fungi and viruses, and staphylococcus can slowly develop resistance to lincomycin. 2. Sulfonamide antimicrobials: the drug is used for the prevention and treatment of bacterial infectious chemical drugs, with a wide antibacterial spectrum, rapid oral absorption and other advantages. Clinical application of infectious diseases, such as urinary tract infections, otitis media, streptococcus pneumoniae, respiratory tract infections, parasitic infections, complicated urinary tract infections. Points to note: Lincomycin can cause gastrointestinal reactions, elevated aminotransferase, and requires regular blood tests and liver function. The drug is prohibited for those who are allergic to sulfa drugs and patients with megaloblastic anemia.