Two packs of cigarettes a day cough for many reasons, commonly found in chronic pharyngitis, chronic bronchitis, lung cancer and so on. 1. Chronic pharyngitis: chronic pharyngitis is a chronic diffuse inflammation of the pharyngeal mucosa and submucosal tissues. Smoking can stimulate the pharyngeal mucosa, aggravate the inflammatory response, and cause patients to cough. Cefuroxime, azithromycin and other drugs can be used for treatment as prescribed by the doctor. 2. Chronic bronchitis: chronic bronchitis is a chronic non-specific inflammation of the bronchial mucosa and surrounding tissues, smoking will stimulate the bronchial secretion increase, causing patients to cough. Daily smoking cessation is needed, and when there is evidence of bacterial infection, levofloxacin, compound licorice tablets, aminoglutethimide hydrochloride and other drugs can be used as prescribed by the doctor. 3. Lung cancer: there is clear evidence that smoking is closely related to lung cancer, and the possibility of lung cancer should be highly suspected when there is long-term smoking history and unexplained severe cough. Timely surgery and radiotherapy are needed. If the symptoms of coughing after smoking appear, it is recommended to go to the hospital in time to find out the cause of the disease and carry out standardized treatment under the guidance of the doctor. In addition, smoking is harmful to health, it is recommended to quit smoking as soon as possible.