The above clinical manifestations may be caused by the following diseases: 1. Severe pneumonia, which can lead to aggravation of cough and sputum at night, can be diagnosed clearly by improving lung CT, blood tests and other related tests. 2. Cough variant asthma can also be aggravated by coughing and sputum at night, and we can clarify the diagnosis by improving the bronchodilator test, lung function and other related tests. Inhaled glucocorticosteroids, such as Symbicort or Sulforaphane, and oral leukotriene modulators, such as Montelukast. 3. Cardiac insufficiency can also cause nocturnal cough and sputum, and we can make a clear diagnosis by improving electrocardiogram, cardiac ultrasound, cardiac enzymes, cardiac natriuretic and other related tests.