HPV generally refers to human papillomavirus infection. HPV positive can be observed if asymptomatic, regular review can be, some patients can be self-cured within six months. If there are obvious symptoms, it can be treated by drugs, surgery, physical methods, etc. It is recommended that patients go to the hospital in time. 1. Drug treatment: use retinoic acid to promote epidermal cell renewal and improve keratinized lesions caused by HPV infection; or use fluorouracil to improve hyperplastic lesions caused by HPV infection, or use imiquimod to help local immune regulation. 2. Surgery: For laryngeal papillomas or high-grade intraepithelial lesions of the genital tract with a high risk of cancer, etc., surgical excision can be performed. 3. Physical therapy: It can be used for smaller lesions by means of CO₂ laser, high-frequency electrosurgical knife treatment, microwave, and liquid nitrogen freezing to necrolyze and detach the lesions. Human papillomavirus infection suggests that patients can be treated according to the situation.