Gout big toe pain may be caused by uric acid crystals, gout stones causing local inflammation or compression of adjacent tissues. Gout big toe pain is due to the elevated concentration of urates in the blood, resulting in the precipitation of urates to form crystalline deposits in the big toe area, on the one hand, urate crystals will cause a local inflammatory reaction, inflammation and stimulation will lead to redness, swelling and pain in the big toe. On the other hand, urate deposition to form gout stones will compress the local nerve tissue, damage the joints, thus causing local pain symptoms. Gout is a chronic and serious disease, gout caused by arthropathy can not be reversed, which can lead to a decline in the patient’s quality of life, gout caused by acute pain attacks in the big toe can be used ibuprofen tablets, colchicine tablets, etc. to control the local inflammatory reaction, reduce the patient’s symptoms. Please follow the doctor’s instructions for specific medication, and do not take it on your own. Gout big toe pain is intense patients, should go to the hospital in a timely manner, under the guidance of the doctor for standardized treatment, to prevent further progression of the disease.