Lumbar spine instability generally does not heal on its own. Lumbar spine instability refers to the pathological changes that occur when the lumbar vertebrae cannot maintain the normal positional relationship with each other under the normal postural load. Under such conditions, lumbar spine instability will produce a series of symptoms, such as recurrent lumbar pain and radiating pain in the lower limbs. Lumbar spine instability generally can not be cured by itself, need to be actively treated, in favor of improving the symptoms, mild symptoms can be treated conservatively, such as braking, the application of non-steroidal anti-inflammatory drugs, such as diclofenac sodium, etc., such as the emergence of severe lumbar pain or severe nerve compression symptoms, conservative treatment is ineffective, feasible surgery, such as lumbar spine implantation of fusion of internal fixation and so on. Lumbar spine instability, such as recurrent lumbar pain or lower extremity radiating pain, should go to the hospital for further diagnosis and treatment in a timely manner, do not be negligent, so as not to delay the condition. Drugs should be applied according to the doctor’s prescription.