Whether liver cysts and kidney cysts can be operated at the same time needs to be decided according to the actual situation. When liver cysts and kidney cysts have no obvious symptoms and do not meet the surgical indications, they do not need surgery and can be treated conservatively with medication for the time being; when there is a change in the condition that necessitates surgery, the decision to operate at the same time should be made based on the results of the actual tests such as puncture, CT, ultrasound, and routine blood tests. If one of them is large and the other one is small, the larger one is usually chosen first for single surgery; if both of them have reached the indication for surgery and the patient’s own physical condition allows it, then both of them can be operated at the same time. Both liver cysts and kidney cysts need to be examined regularly to determine the nature of the cysts when their condition changes and to choose the appropriate treatment according to the physician’s instructions.