Acne is the most common inflammation of the sebaceous glands of the hair follicles during puberty. And some people will appear on the face of a grain and acne looks very similar to the small bumps, but these are not acne, but the performance of certain skin diseases: 1, occupational acne and engaged in occupations and work environment is closely related, such as long-term exposure to gasoline, diesel fuel, a variety of lubricating oils, paraffin wax, chlorine-containing compounds, etc., easy to cause occupational acne. The distribution of the rash has its own characteristics, the typical parts are near the eyes, cheekbones, but also in the perineum, the back of the hands, limbs and trunk and other parts. Commonly, there are blackheads and folliculitis, and some people feel itchy. If the blackheads acne, can make the skin become gray; folliculitis heavy caused by pustules, can leave scars, affecting the appearance of beauty. 2, follicular dermatitis is a chronic inflammation caused by follicular parasites in the skin follicles or skin glands, oily skin people are prone to occur. Facial erythema on the appearance of pimples, pustules, can be crusted, flaking, without acne. 3, acne-like drug rash caused by certain drugs, such as taking iodine, bromine, isoniazid, corticosteroids, etc., the skin and trunk can appear follicular pimples, pustules, after stopping the drug can disappear on its own. 4, rosacea-like tuberculosis rash associated with the infection of tuberculosis bacillus, face view of the Department of erythema, capillary dilatation, rash such as the size of a grain of corn, presenting light red or yellowish brown. 5.Clusters of periorbital acne In the lateral side of the eyelid and zygomatic bone area, there are clusters of larger acne, mostly occurring in men and women aged 30-50 years old. Ray elastosis is present in most of the patients.