Clinical instructions for Si Shen Wan clearly state that it should be taken one to two times a day, so it should not be taken three times a day. Four Spirits Pill is composed of simmered nutmeg, salt-fried boneset, vinegared schizandra, cornelian cherry, and de-veined jujube, which has the efficacy of warming the kidneys, dispersing cold, astringing the intestines and stopping diarrhea (relieving diarrhea by enhancing the intestinal astringent function). Clinically, this product is often used in the treatment of diarrhea caused by deficiency of kidney yang, with symptoms of intestinal tinnitus and abdominal distention, loose bowel movements, poor appetite, and prolonged diarrhea. The instructions clearly record that Si Shen Wan should be taken one to two times a day, so it should not be taken three times a day. Si Shen Wan is prohibited for allergy, adverse reactions, contraindications and precautions are not clear, patients who are taking other drugs should consult a doctor in advance, so as not to affect the efficacy of drug interactions. It is recommended that patients take Sishen Pills in strict compliance with the doctor’s instructions, do not increase the amount of private, so as to avoid the adverse consequences of drug overdose.