Pimples on the cheeks are usually considered to be acne, which is related to abnormal secretion of sex hormones in the body, increased secretion of hair follicles, and propagation of Propionibacterium folliculorum. 1. Abnormal secretion of sex hormones in the body: Excessive secretion of androgens in the body, or abnormal metabolism of estrogen androgen can easily induce acne. 2. Increased secretion of sebaceous glands and keratinization of hair follicles can easily cause acne. 3. Propionibacterium folliculorum multiplication: large number of Propionibacterium folliculorum multiply in the hair follicle, forming inflammatory reaction is also easy to cause acne. 4. Other factors: staying up late, working hard, smoking, taking spicy food, eating too oily and sweet products, and genetic factors are also related. Acne should be treated promptly and in accordance with medical advice.