Postherpetic neuralgia is generally referred to as postherpetic neuralgia, which refers to the persistence of neuralgia after the healing of herpes zoster lesions, and the medications that can be used for this purpose are Pregabalin, Phenytoin sodium, and Loxoprofen sodium. 1. Pregabalin: used in the treatment of postherpetic neuralgia. Pregabalin has the effect of inhibiting GABAA, GABAB or benzodiazepine receptors, which can relieve the pain. 2. Phenytoin sodium: Phenytoin sodium can promote the efflux of Na ions from the cells and reduce the inward flow of Na ions, thus stabilizing the nerve cell membrane, raising the excitation threshold, and reducing the high-frequency discharges in the lesion area, thus relieving neuralgia. 3. Loxoprofen sodium: a non-steroidal anti-inflammatory drug with anti-inflammatory, antipyretic and analgesic effects, through the inhibition of cyclo-oxygenase, thereby inhibiting the conversion of arachidonic acid into prostaglandins to alleviate the role of pain. If the sequelae of shingles, persistent unrelieved, need to promptly to the hospital, follow the doctor’s instructions standardized treatment, the use of drugs must follow the doctor’s instructions implementation.