Epididymitis is a non-specific inflammation of the male epididymis caused by Escherichia coli, staphylococcus and other pathogenic bacteria infection, in the acute exacerbation of antimicrobial treatment, you can use cephalosporins. Acute epididymitis requires active antimicrobial treatment, often based on drug sensitivity tests to select drugs sensitive to bacteria, cephalosporins, macrolides, quinolones are commonly used in the clinic, such as ceftazidime, levofloxacin, tetracycline and so on. Epididymitis caused by sexual transmission is mainly treated with cephalosporins, and levofloxacin can also be used in combination if necessary. Epididymitis patients in the acute onset of the disease, should try to bed rest, avoid physical labor and sexual life, but also through the cold or hot compresses to relieve the discomfort.