Some scholars have found that people with HBV infection, have a high incidence of diabetes, with a 25% incidence of type 2 diabetes among foreign viral adults with chronic hepatitis B; four times that of the general population. The prevalence of diabetes among HBV-infected and non-HBV-infected individuals in Asian populations was 65% and 27.5%, respectively. However, type 2 diabetes was found to be independent of HBV infection in studies in Taiwan and Hong Kong. A survey of 2303 chronic hepatitis B patients in Beijing found that 10.25% had diabetes, suggesting that the occurrence of diabetes may be related to HBV infection. Further research is needed on the correlation and mechanism of chronic HBV infection and diabetes. Cirrhosis and diabetes mellitus: The chance of diabetes mellitus increases significantly in chronic HBV and HCV infected patients after entering the cirrhotic stage. It has been reported that 96% of cirrhotic patients have abnormal glucose tolerance and 30% have significant diabetes mellitus. Further studies have found that abnormal glucose tolerance already exists in patients at the compensated stage of cirrhosis. Some domestic hepatologists call this kind of diabetes that occurs on the basis of chronic liver disease cirrhosis: “hepatogenic diabetes”, and even classify it as one of the complications of liver cirrhosis. Its pathogenesis is related to the decrease of insulin resistance glucose metabolizing enzyme activity caused by liver insufficiency.