Cocaine extended-release tablets are mainly used for the improvement of cerebral circulation after ischemic cerebrovascular disease, as well as for the treatment of peripheral vascular diseases, such as chronic occlusive vasculitis with intermittent claudication. The drug is a non-specific peripheral vasodilator that dilates isolated canine basilar arteries. The use of the drug may cause adverse reactions such as headache, dizziness, bloating, diarrhea, nausea, vomiting, allergy. Care should be taken when using the drug, it should be used with caution in people with hypotension, unstable blood pressure or severe disorders of renal function. The drug is contraindicated in patients with acute myocardial infarction, severe coronary atherosclerosis, cerebral hemorrhage, retinal hemorrhage, as well as in those who are allergic to the product. The drug needs to be used under the guidance of a doctor.