Pressure sores, also called bedsores, are caused by long-term pressure on the affected area, local ischemia and hypoxic necrosis of soft tissues, which in turn lead to the formation of ulcers. When pressure sores cause infection and fever, general treatment, drug treatment (amoxicillin, etc.), physical therapy (infrared irradiation, etc.) and surgical treatment (debridement) are given according to the condition. 1. General treatment: patients need to turn over diligently to reduce the pressure on the affected area, can massage the affected area and the surrounding soft tissues to promote local blood circulation, which is conducive to wound healing. Patients with fever need to maintain indoor ventilation and drink more water. 2. medication: need to give relevant antibacterial drug treatment, such as amoxicillin, levofloxacin, etc., anaerobic infections can be given metronidazole and other treatment. Fever patients with body temperature higher than 38.5 degrees can be given ibuprofen and other cooling drugs. Specifically, you can also use erythromycin ointment and other antibacterial drugs, recombinant human epidermal growth factor to promote healing. 3. Physical therapy: local infrared irradiation therapy, hot compresses, etc., can promote local blood circulation, which is conducive to promoting the healing of the wound. 4. Surgical treatment: thorough debridement of the wound is needed to remove necrotic tissues and secretions from the wound, and use iodophor, alcohol and other disinfectants to thoroughly disinfect the wound. For patients with large skin defects, skin grafting can also be given if necessary. It is recommended that patients seek medical treatment in a timely manner, according to the patient’s condition, by a professional physician to give the appropriate treatment, the drug has more adverse reactions and contraindications, so it is necessary to use under the guidance of a professional physician.