1, muscle and soft tissue chronic pain, this type of pain and myofasciitis, tenosynovitis, frozen shoulder and chronic lumbar muscle strain. 2, bone and joint pain, common knee arthritis, ankylosing spondylitis, sacroiliac arthritis, rheumatoid arthritis, rheumatoid arthritis, gouty arthritis, cervical disc herniation and lumbar disc herniation, etc. 3, headache, headache is a common chronic painful disease, its etiology and pathophysiology is complex, divided into two categories of primary pain and secondary headache. 4, neuropathic pain, a chronic pain caused by neurological injury, for example: trigeminal neuralgia, postherpetic neuralgia, Raynaud’s syndrome, thrombo-occlusive vasculitis, etc. 5, spinal-derived pain, pain caused by spinal-related structural lesions. Such as lumbar disc herniation, cervical spondylosis, spondylolisthesis, etc. 6. chronic pain after trauma, severe trauma and postoperative pain can migrate to chronic pain if not treated effectively in time. 7. certain non-painful diseases such as facial nerve dysfunction, intractable disobedience, indeterminate statement syndrome, etc., take a nerve block-based comprehensive treatment, which has certain efficacy. Therefore, pain clinics also often admit such patients. 7, vascular pain, such as arteriosclerosis occlusion, erythema limb pain, Raynaud’s disease, etc. 8.Cancer pain, late stage cancer pain includes multiple pathogenic factors triggering pain.